Review



endogenous cyr61  (R&D Systems)


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    Structured Review

    R&D Systems endogenous cyr61
    ( A ) Experimental setup. ( B ) Representative images of Safranin-O-staining and ( C ) quantitative measurement of chondrogenic pellet diameter at 2 weeks. ( D ) Relative mRNA expression of RUNX2, SP7, COL1A1 and <t>CYR61</t> after 3 weeks of osteogenic differentiation normalized to housekeeping gene and control. ( E ) 3D in vitro angiogenesis assay combing HUVECs and hMSCs. ( F ) Exemplary images of tube formation at 3 days. ( G ) Quantification of relative GFP+ cell area, relative tube number and tube length. Mean ± SEM and individual data points. One-way ANOVA was used to determine the statistical significance; p-values are indicated with *p < 0 . 05; **p < 0 . 01; ***p < 0 . 001 . Scale bars indicate 500 μm (B) and 200 μm (F).
    Endogenous Cyr61, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 9 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/endogenous cyr61/product/R&D Systems
    Average 94 stars, based on 9 article reviews
    endogenous cyr61 - by Bioz Stars, 2026-02
    94/100 stars

    Images

    1) Product Images from "Cyr61 delivery promotes angiogenesis during bone fracture repair"

    Article Title: Cyr61 delivery promotes angiogenesis during bone fracture repair

    Journal: bioRxiv

    doi: 10.1101/2024.04.05.588239

    ( A ) Experimental setup. ( B ) Representative images of Safranin-O-staining and ( C ) quantitative measurement of chondrogenic pellet diameter at 2 weeks. ( D ) Relative mRNA expression of RUNX2, SP7, COL1A1 and CYR61 after 3 weeks of osteogenic differentiation normalized to housekeeping gene and control. ( E ) 3D in vitro angiogenesis assay combing HUVECs and hMSCs. ( F ) Exemplary images of tube formation at 3 days. ( G ) Quantification of relative GFP+ cell area, relative tube number and tube length. Mean ± SEM and individual data points. One-way ANOVA was used to determine the statistical significance; p-values are indicated with *p < 0 . 05; **p < 0 . 01; ***p < 0 . 001 . Scale bars indicate 500 μm (B) and 200 μm (F).
    Figure Legend Snippet: ( A ) Experimental setup. ( B ) Representative images of Safranin-O-staining and ( C ) quantitative measurement of chondrogenic pellet diameter at 2 weeks. ( D ) Relative mRNA expression of RUNX2, SP7, COL1A1 and CYR61 after 3 weeks of osteogenic differentiation normalized to housekeeping gene and control. ( E ) 3D in vitro angiogenesis assay combing HUVECs and hMSCs. ( F ) Exemplary images of tube formation at 3 days. ( G ) Quantification of relative GFP+ cell area, relative tube number and tube length. Mean ± SEM and individual data points. One-way ANOVA was used to determine the statistical significance; p-values are indicated with *p < 0 . 05; **p < 0 . 01; ***p < 0 . 001 . Scale bars indicate 500 μm (B) and 200 μm (F).

    Techniques Used: Staining, Expressing, Control, In Vitro, Angiogenesis Assay



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    94
    R&D Systems endogenous cyr61
    ( A ) Experimental setup. ( B ) Representative images of Safranin-O-staining and ( C ) quantitative measurement of chondrogenic pellet diameter at 2 weeks. ( D ) Relative mRNA expression of RUNX2, SP7, COL1A1 and <t>CYR61</t> after 3 weeks of osteogenic differentiation normalized to housekeeping gene and control. ( E ) 3D in vitro angiogenesis assay combing HUVECs and hMSCs. ( F ) Exemplary images of tube formation at 3 days. ( G ) Quantification of relative GFP+ cell area, relative tube number and tube length. Mean ± SEM and individual data points. One-way ANOVA was used to determine the statistical significance; p-values are indicated with *p < 0 . 05; **p < 0 . 01; ***p < 0 . 001 . Scale bars indicate 500 μm (B) and 200 μm (F).
    Endogenous Cyr61, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/endogenous cyr61/product/R&D Systems
    Average 94 stars, based on 1 article reviews
    endogenous cyr61 - by Bioz Stars, 2026-02
    94/100 stars
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    ( A ) Experimental setup. ( B ) Representative images of Safranin-O-staining and ( C ) quantitative measurement of chondrogenic pellet diameter at 2 weeks. ( D ) Relative mRNA expression of RUNX2, SP7, COL1A1 and CYR61 after 3 weeks of osteogenic differentiation normalized to housekeeping gene and control. ( E ) 3D in vitro angiogenesis assay combing HUVECs and hMSCs. ( F ) Exemplary images of tube formation at 3 days. ( G ) Quantification of relative GFP+ cell area, relative tube number and tube length. Mean ± SEM and individual data points. One-way ANOVA was used to determine the statistical significance; p-values are indicated with *p < 0 . 05; **p < 0 . 01; ***p < 0 . 001 . Scale bars indicate 500 μm (B) and 200 μm (F).

    Journal: bioRxiv

    Article Title: Cyr61 delivery promotes angiogenesis during bone fracture repair

    doi: 10.1101/2024.04.05.588239

    Figure Lengend Snippet: ( A ) Experimental setup. ( B ) Representative images of Safranin-O-staining and ( C ) quantitative measurement of chondrogenic pellet diameter at 2 weeks. ( D ) Relative mRNA expression of RUNX2, SP7, COL1A1 and CYR61 after 3 weeks of osteogenic differentiation normalized to housekeeping gene and control. ( E ) 3D in vitro angiogenesis assay combing HUVECs and hMSCs. ( F ) Exemplary images of tube formation at 3 days. ( G ) Quantification of relative GFP+ cell area, relative tube number and tube length. Mean ± SEM and individual data points. One-way ANOVA was used to determine the statistical significance; p-values are indicated with *p < 0 . 05; **p < 0 . 01; ***p < 0 . 001 . Scale bars indicate 500 μm (B) and 200 μm (F).

    Article Snippet: Different concentrations of endogenous Cyr61 (0-200 ng/ml; Recombinant Human Cyr61/CCN1 Fc Chimera Protein, carrier-free; catalog no.: 4055-CR; R&D Systems, Minneapolis, MN) and TGFβ (0 or 10 ng/ml; rhTGF-beta1; R&D Systems, Minneapolis, MN) were added to the medium.

    Techniques: Staining, Expressing, Control, In Vitro, Angiogenesis Assay